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Sponge Monolith: Olefin-based thermoplastic porous plastic

A new high water permeability separator with a monolithic structure that allows for high-speed liquid delivery. Ideal for pretreatment and concentration agents!

The thermoplastic general-purpose polymer (ethylene-vinyl acetate copolymer: EVA) has been used for the first time as a novel medium for chromatography. It is a soft material like a sponge, with several tens of microns of through-holes, making it an excellent monolithic separation agent with high permeability. The sponge monolith has a significant capacity for retaining planar molecules, and applications that leverage its unique separation characteristics are anticipated. Additionally, by hydrolyzing the vinyl acetate portion of the EVA sponge monolith, hydroxyl groups can be generated on the surface, allowing for chemical modification and the creation of functional separation agents. Expected applications and uses Applications as media for protein separation in reverse phase and ion exchange modes are anticipated. In particular, sponge monoliths with ion exchange or affinity functions could serve as low-cost, high-permeability alternative separation media for protein purification. Furthermore, the sponge monolith can improve loading capacity and selectivity through hybridization (by adding insoluble functional materials during mixing).

  • Analytical Equipment and Devices

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